Neutron studies of HIV inhibitors reveal new areas for improvement
The first study of interactions between a common clinical inhibitor and the HIV-1 protease enzyme has been carried out by an international team with members from the US, Britain and France using neutrons at the Institut Laue-Langevin in Grenoble, France. It provides medical science with the first true picture of how an antiviral drug used to block virus replication actually works, and critically how its performance could be improved. The findings, reported in the Journal for Medicinal Chemistry , and the neutron techniques demonstrated at the ILL, will provide the basis for the design of a new generation of more effective pharmaceuticals to address issues such as drug resistance.
YSU's research reputation grows 'diffractometer by diffractometer' Ι ...
“One of the wonderful things about this instrumentation coming to YSU, as opposed to what you might see on other campuses, is that we’re going to have the ability for undergraduates to access this diffractometer, to be able to use it, have... Here, our undergraduates get a level of exposure that provides a means for them to go into the workforce with the experience that many other students at many other places will not have. “At other places, it might just be doctoral students or graduate students who get access to this level of equipment. Ryan announced at a news conference that the National Science Foundation had awarded a $470,000 grant to YSU to purchase two high-end X-ray diffractometers, which allows research of materials on the atomic level.
Observation of quadrupole helix chirality and its domain structure in DyFe 3 ...
- While one of the workhorse-instruments at the Lujan Center, HIPPO is a general-purpose powder diffractometer that measures both the crystal structure and orientation distribution of crystals (or texture) making up a poly-crystalline material from the
- Measurements on the polished surface of the two specimens were carried out using an ultrahigh-vacuum diffractometer equipped at the beamline 17SU, SPring-8, Japan33. The incident photon energy was tuned approximately to the Dy M5 edge (=1,292 eV).
- As mineralogical information is not available from XRF spectra, wet chemical methods such as titration or separate X-ray diffractometry (XRD) equipment is required to determine the phase content in clinker or cement. The Thermo Scientific ARL 9900